WebNov 1, 2013 · However, the previous studies were conducted on the facial bone 8 and measured only serum markers of osteogenesis, not bone mineral density.6, 7 To our knowledge, no studies focusing on the association between phenytoin level and bone mineral density at other sites, specifically the lumbar spine and femoral neck, and … WebNov 12, 2024 · SGLT-2 inhibitors may reduce bone density at the hip and increase fracture risk, although data are conflicting. Both type 1 and type 2 diabetes are associated with increased risk of breaking a bone. Bone density is usually lower than average in people with type 1 diabetes but higher than average in people with type 2 diabetes.
Osteopenia: Treatment, Symptoms, Diet, and Diagnosis - Healthline
WebSep 9, 2024 · Examples of anticonvulsants that may harm bones: Phenytoin (Dilantin) Phenobarbital (Luminal) Valproic acid (Depakote) The key takeaway for bone health: Talk to your doctor about taking a... WebApr 1, 2003 · Men and women reach peak bone density by their early 20s. 5 Peak bone density is ... Men taking phenytoin or phenobarbital also should take supplemental calcium and vitamin D and be considered for ... feed io
Anti-epileptic drugs and osteoporosis Royal Osteoporosis
WebMay 26, 2024 · Decreased bone mineral density (vitamin D deficiency) Dermatologic reactions, including Stevens-Johnson Syndrome (SJS) and Toxic Epidermal Necrolysis (TEN) Hepatotoxicity. Peripheral neuropathy. Phenytoin Dose-Dependent Adverse Effects (aka indications of phenytoin toxicity) Nausea/vomiting (early) Nystagmus. Ataxia WebPhenytoin sodium is poorly soluble in water and is available as a parenteral preparation containing 50 mg/ml formulated in 40% propylene glycol and 10% ethanol with the pH … WebOct 18, 2024 · Long-term use in patients with epilepsy associated with decreased bone mineral density (BMD) and related bone effects (e.g., osteopenia, osteoporosis, osteomalacia, fractures). Thought to be caused by phenytoin’s interference with vitamin D … feed into your sleepiness